The Titan will get you where you want EQ-wise because it's all mids - there's not a whole lot of bass to get flabby and not a whole lot of treble to get harsh. The caveat to this is that it's also a super 'dry' feeling pickup (not a lot of compression, you need to be picking hard all the time if you want output and aggression) and it's very modern-voiced which I know some people aren't into. The neck version is similar, but a bit brighter and with a bit more compression. IMO it actually really shines in parallel mode (position 4 on the JB Ibanez) for cleans and leads.
It's a decently dark set overall, but still very present and cutting due to the mid focus, and it'll definitely push an amp pretty well. I've played it in a parts Tele and in the JB Ibanez (the latter of which is pretty LP-like - mahogany body, chunky maple top, maple-mahogany neck, and ebony board).