It is probably the closest single coil sized humbucker to it's full sized counterpart.
I have an air Norton in my rg520qs and an ANs in my rg3xxv (HS config like yours)
The ANs is about the same output as the AN.
The ANs is a bit brighter and tighter, but still not what I would call a bright pickup. More warm but clear.
I have only used it in this guitar and love it. It may be to warm/ muddy for a 22fret neck position. 24 feet is great.
Since I like the Norton in the bridge, I wouldn't hesitate to use it there too.